Product ID:CHLOROMYCETIN HYDROCORTISONE OPHTHALMIC
MSDS Date:05/21/1991
FSC:6505
NIIN:00F027365
MSDS Number: BQZKP

Emergency Phone: 201-540-2000

Info Phone: 201-540-2000

Preparer: ROY MUELLER

Cage: 82559

Telephone: 201-540-2000

Cage: 82559

CHLORAMPHENICOL (SUSPECTED HUMAN CARCINOGEN BY IARC)

CAS: 56-75-7

RTECS: AB6825000

HYDROCORTISONE ACETATE

CAS: 50-03-3

RTECS: GM8960000

Routes of Entry: Inhalation:YES Skin:YES Ingestion:NO
Reports of Carcinogenicity:NTP:NO IARC:YES OSHA:NO
Health Hazards Acute and Chronic:SKIN: MILD SENSITIZATION (MACULAR
RASHES). REFER TO CURRENT PACKAGE INSERT FOR FURTHER INFORMATION.
Explanation of Carcinogenicity:SEE INGREDIENTS
Effects of Overexposure:THERAPEUTIC ADVERSE REACTIONS INCLUDE BONE
MARROW DEPRESSION, SERIOUS & FATAL BLOOD DYSCRASIAS (APLASTIC
ANEMIA, HYPOPLASTIC ANEMIA, THROMBOCYTOPENIA & GRANULOCYTOPENIA),
GASTROINTESTINAL & CNS DISTUR BANCES. MARROW DEPRESSION CAN BE
REVERSIBLE (DOSE RELATED) & IRREVERSIBLE (NOT DOSE RELATED). SEE
SUPPLEMENTAL DATA.

First Aid:EYES: FLUSH W/WATER FOR 15 MINS. SKIN: WASH W/SOAP & WATER
UNTIL FREE OF RESIDUE. INHALATION: REMOVE TO FRESH AIR. INGESTION:
OBTAIN MEDICAL ATTENTION IN ALL CASES.

Extinguishing Media:CO2, DRY CHEMICAL, FOAM, WATER SPRAY
Fire Fighting Procedures:USE APPROVED SELF CONTAINED BREATHING
APPARATUS.

Spill Release Procedures:WIPE OR MOP UP SPILLED MATERIAL. WASH ALL
CONTAMINATED SURFACES W/SOAP & WATER. PLACE WASTE IN APPROPRIATE
CONTAINER FOR FUTURE DISPOSAL.

Handling and Storage Precautions:STORE AS STATED IN PRODUCT LABELING.
WHEN HANDLING DRY CAKE, USE HANDLING METHOD TO MINIMIZE DUST
GENERATION.
Other Precautions:MATERIAL SHOULD BE HANDLED IN SUCH A WAY AS TO AVOID
SKIN & EYE CONTACT.

Work Hygienic Practices:WASH EXPOSED SKIN PROMPTLY. REMOVE/LAUNDER
CONTAMINATED CLOTHING & WASH CONTAMINATED PROTECTIVE EQUIPMENT
BEFORE REUSE.
Supplemental Safety and Health
OVEREXPOSURE CON'T: THERE HAVE BEEN REPORTS OF APLASTIC ANEMIA
ATTRIBUTED TO CHLORAMPHENICOL WHICH LATER TERMAINATED IN LEUKEMIA.

Spec Gravity:1.011
Solubility in Water:COMPLETE
Appearance and Odor:WHITE TO OFF-WHITE CAKE

Stability Indicator/Materials to Avoid:YES
Hazardous Decomposition Products:CO, CO2, NITROGEN, & HYDROGEN CHLORIDE

Waste Disposal Methods:DISPOSE OF IN ACCORDANCE W/LOCAL, STATE, &
FEDERAL REGULATIONS. INCINERATION IN A PERMITTED INCINERATOR IS THE
PREFERRED DISPOSAL METHOD.

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.